View source for 9enb


==Human pseudouridine synthase 3 (PUS3 R116A mutant) and two tRNA-Gln==
<StructureSection load='9enb' size='340' side='right'caption='[[9enb]], [[Resolution|resolution]] 2.66&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9enb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ENB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ENB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.66&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9enb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9enb OCA], [https://pdbe.org/9enb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9enb RCSB], [https://www.ebi.ac.uk/pdbsum/9enb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9enb ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/PUS3_HUMAN PUS3_HUMAN] Severe growth deficiency-strabismus-extensive dermal melanocytosis-intellectual disability syndrome. The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/PUS3_HUMAN PUS3_HUMAN] Formation of pseudouridine at position 39 in the anticodon stem and loop of transfer RNAs.<ref>PMID:27055666</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Glatt S]]
[[Category: Jezowski J]]
[[Category: Lin T-Y]]