View source for 9nwb


==Crystal structure of SARS-CoV-2 main protease in complex with an inhibitor TKB-280-5I==
<StructureSection load='9nwb' size='340' side='right'caption='[[9nwb]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9nwb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus Severe acute respiratory syndrome coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9NWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9NWB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1B7A:(1~{R},2~{S},5~{S})-3-[(2~{S})-3,3-dimethyl-2-[2,2,2-tris(fluoranyl)ethanoylamino]butanoyl]-~{N}-[(2~{R})-1-(5-iodanyl-1,3-benzothiazol-2-yl)-1-oxidanyl-3-[(3~{R})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide'>A1B7A</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9nwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9nwb OCA], [https://pdbe.org/9nwb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9nwb RCSB], [https://www.ebi.ac.uk/pdbsum/9nwb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9nwb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A8B1JK87_SARS2 A0A8B1JK87_SARS2] 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Severe acute respiratory syndrome coronavirus]]
[[Category: Bulut H]]
[[Category: Das D]]
[[Category: Hattori S]]
[[Category: Hayashi H]]
[[Category: Li M]]
[[Category: Mitsuya H]]
[[Category: Tamamura H]]
[[Category: Wlodawer A]]