View source for UvrABC


<StructureSection load='3pih' size='340' side='right' caption='UvrA complex with DNA, pyrophosphate and Zn+2 ion (grey) [[3pih]]' scene='' >
'''UvrABC''' endonuclease is an ''E. coli'' enzyme complex involved in DNA repair.  UvrABC removes 12 nucleotides around a DNA mutation replacing them with the correct one.  For details on the UvrA-UvrB complex see [[UvrA-UvrB interaction domains]].
</StructureSection>
==3D structures of UvrABC==

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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*UvrA

**[[3pih]] – TmUvrA + DNA – ''Thermotoga maritima'' <br />
**[[3zqj]] – UvrA  – ''Mycobacterium tuberculosis''<br />
**[[4dfc]] – EcUvrA + Transcription-repair-coupling factor – ''Escherichia coli'' <br />
**[[2r6f]] – BstUvrA – ''Bacillus stearothermophilus'' <br />
**[[3ux8]] – GeUvrA - ''Geobacillus''<br />

*UvrB

**[[1d2m]], [[1c4o]] – UvrB – ''Thermus thermophilus'' <br />
**[[1d9x]] – BcUvrB – ''Bacillus caldotenax'' <br />
**[[1t5l]] – BcUvrB (mutant) <br />
**[[1qoj]] – EcUvrB C terminal <br />
**[[1e52]] – EcUvrB C terminal - NMR<br />
**[[1d9z]] – BcUvrB + ATP <br />
**[[2fdc]] – BcUvrB + DNA <br />
**[[2d7d]], [[2nmv]], [[3v4r]] – BsUvrB + DNA – ''Bacillus subtilis'' <br />

*UvrC

**[[1kft]] – EcUvrC C terminal <br />
**[[2nrr]], [[2nrt]], [[2nrv]], [[2nrw]], [[2nrx]], [[2nrz]] – TmUvrC C terminal <br />
**[[1ycz]], [[1yd0]], [[1yd1]] – TmUvrC N terminal <br />
**[[1yd2]], [[1yd3]], [[1yd4]], [[1yd5]] – TmUvrC N terminal (mutant)<br />
**[[1yd6]] – BcUvrC N terminal <br />
**[[3c65]] – BstUvrC  <br />

*UvrA-UvrB

**[[3fpn]] – BstUvrA + UvrB <br />
**[[3uwx]] – GeUvrA + UvrB <br />
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==References==
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[[Category:Topic Page]]