View source for 6axe


==Crystal structure of a malate synthase G from Mycobacterium marinum bound to acetyl CoA==
<StructureSection load='6axe' size='340' side='right' caption='[[6axe]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6axe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycmm Mycmm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AXE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AXE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">glcB, MMAR_2713 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216594 MYCMM])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Malate_synthase Malate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.9 2.3.3.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6axe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6axe OCA], [http://pdbe.org/6axe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6axe RCSB], [http://www.ebi.ac.uk/pdbsum/6axe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6axe ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/MASZ_MYCMM MASZ_MYCMM]] Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA. 
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</StructureSection>
[[Category: Malate synthase]]
[[Category: Mycmm]]
[[Category: Structural genomic]]
[[Category: Coenzyme some]]
[[Category: Cofactor]]
[[Category: Glcb]]
[[Category: Hydrolase]]
[[Category: Niaid]]
[[Category: Ssgcid]]