View source for 2ce4

[[Image:2ce4.jpg|left|200px]]

 {{Structure
|PDB= 2ce4 |SIZE=350|CAPTION= <scene name='initialview01'>2ce4</scene>, resolution 2.20&Aring;
|SITE= <scene name='pdbsite=AC1:Mn+Binding+Site+For+Chain+B'>AC1</scene>
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span>
|GENE= 
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ce4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ce4 OCA], [http://www.ebi.ac.uk/pdbsum/2ce4 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ce4 RCSB]</span>
}}

'''MANGANESE SUPEROXIDE DISMUTASE (MN-SOD) FROM DEINOCOCCUS RADIODURANS'''


==Overview==
The structure of the manganese superoxide dismutase (Mn-SOD; DR1279) from Deinococcus radiodurans has been determined in two different crystal forms. Both crystal forms are monoclinic with space group P2(1). Form I has unit-cell parameters a = 44.28, b = 83.21, c = 59.52 angstroms, beta = 110.18 degrees and contains a homodimer in the asymmetric unit, with structure refinement (R = 16.8%, R(free) = 23.6%) carried out using data to d(min) = 2.2 angstroms. Form II has unit-cell parameters a = 43.57, b = 87.10, c = 116.42 angstroms, beta = 92.1 degrees and an asymmetric unit containing two Mn-SOD homodimers; structure refinement was effected to a resolution of 2.0 angstroms (R = 17.2%, R(free) = 22.3%). The resulting structures are compared with that of Mn-SOD from Escherichia coli, with which they are shown to be essentially isostructural.

==About this Structure==
2CE4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CE4 OCA]. 

==Reference==
Structure of the manganese superoxide dismutase from Deinococcus radiodurans in two crystal forms., Dennis RJ, Micossi E, McCarthy J, Moe E, Gordon EJ, Kozielski-Stuhrmann S, Leonard GA, McSweeney S, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Apr 1;62(Pt, 4):325-9. Epub 2006 Mar 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16582477 16582477]
[[Category: Deinococcus radiodurans]]
[[Category: Single protein]]
[[Category: Superoxide dismutase]]
[[Category: Dennis, R.]]
[[Category: Gordon, E.]]
[[Category: Leonard, G.]]
[[Category: Mccarthy, J.]]
[[Category: Mcsweeney, S.]]
[[Category: Micossi, E.]]
[[Category: Moe, E.]]
[[Category: deinococcus radioduran]]
[[Category: manganese superoxide dismutase]]
[[Category: oxidoreductase]]
[[Category: radiation resistance]]

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