View source for 2fyo

[[Image:2fyo.jpg|left|200px]]<br /><applet load="2fyo" size="450" color="white" frame="true" align="right" spinBox="true" 
caption="2fyo, resolution 2.00&Aring;" />
'''Crystal structure of rat carnitine palmitoyltransferase 2 in space group P43212'''<br />

==Overview==
Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system, that imports fatty acids into mitochondria. The crystal structure of rat, CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped, tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic, insert mediating membrane association.

==About this Structure==
2FYO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Active as [http://en.wikipedia.org/wiki/Carnitine_O-palmitoyltransferase Carnitine O-palmitoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.21 2.3.1.21] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2FYO OCA]. 

==Reference==
A monotopic membrane protein goes solo., Mattevi A, Structure. 2006 Apr;14(4):628-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16615901 16615901]
[[Category: Carnitine O-palmitoyltransferase]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Banner, D.W.]]
[[Category: Benz, J.]]
[[Category: Chomienne, O.]]
[[Category: Gsell, B.]]
[[Category: Hennig, M.]]
[[Category: Mueller, F.]]
[[Category: Roo, E.De.]]
[[Category: Rufer, A.C.]]
[[Category: Stihle, M.]]
[[Category: Thoma, R.]]
[[Category: central six-stranded beta-sheet]]

''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 10:50:45 2007''