View source for 10hm


==Trypanosoma brucei CLK1 kinase domain in complex with a covalent Amidobenzimidazole (AB4) inhibitor==
<StructureSection load='10hm' size='340' side='right'caption='[[10hm]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[10hm]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=10HM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=10HM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1C5R: {N}-(1-{(3 {R})-1-[4-(dimethylamino)butanoyl]azepan-3-yl}-4,6-difluoro-1 {H}-1,3-benzimidazol-2-yl)-5-fluoropyridine-3-carboxamide'>A1C5R</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=10hm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10hm OCA], [https://pdbe.org/10hm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10hm RCSB], [https://www.ebi.ac.uk/pdbsum/10hm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10hm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q382U0_TRYB2 Q382U0_TRYB2] 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Trypanosoma brucei brucei TREU927]]
[[Category: Mamo M]]