View source for 10og


==20S Alpha 3 Deletion proteasome core particle in complex with Fub1 and Blm10==
<StructureSection load='10og' size='340' side='right'caption='[[10og]], [[Resolution|resolution]] 4.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[10og]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=10OG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=10OG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=10og FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10og OCA], [https://pdbe.org/10og PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10og RCSB], [https://www.ebi.ac.uk/pdbsum/10og PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10og ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PSA2_YEAST PSA2_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Fermin Perez E]]
[[Category: Hanna J]]
[[Category: Rawson S]]
[[Category: Venclovaite U]]
[[Category: Walsh Jr RM]]