View source for 10pa


==Crystal structure of SdrD A2-A3 domains from Staphylococcus aureus JH1==
<StructureSection load='10pa' size='340' side='right'caption='[[10pa]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[10pa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_JH1 Staphylococcus aureus subsp. aureus JH1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=10PA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=10PA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=10pa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10pa OCA], [https://pdbe.org/10pa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10pa RCSB], [https://www.ebi.ac.uk/pdbsum/10pa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10pa ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SDRD_STAAM SDRD_STAAM] Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis. Mediates interactions with components of the extracellular matrix such as host DSG1 to promote bacterial adhesion to host cells. Contributes to the resistance to killing by innate immune components such as neutrophils present in blood and thus attenuates bacterial clearance.[UniProtKB:Q2G0L4]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus subsp. aureus JH1]]
[[Category: Endres M]]
[[Category: Gade PR]]
[[Category: Jochimiak A]]
[[Category: Tan K]]