View source for 11st


==Structure of Yarrowia lipolytica ORC-Cdc6 bound to 54bp segment of OriC-061 DNA==
<StructureSection load='11st' size='340' side='right'caption='[[11st]], [[Resolution|resolution]] 2.73&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[11st]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Yarrowia_lipolytica Yarrowia lipolytica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=11ST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=11ST FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.73&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=11st FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=11st OCA], [https://pdbe.org/11st PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=11st RCSB], [https://www.ebi.ac.uk/pdbsum/11st PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=11st ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q6C9L7_YARLI Q6C9L7_YARLI] Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.[RuleBase:RU365058]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Yarrowia lipolytica]]
[[Category: Bauer J]]
[[Category: Joshua-Tor L]]