View source for 13fn


==Thermotoga maritima threonylcarbamoyl transfer complex (TsaB2D) in complex with Escherichia coli tRNA(THR)==
<StructureSection load='13fn' size='340' side='right'caption='[[13fn]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[13fn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=13FN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=13FN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=T6A:N-[N-(9-B-D-RIBOFURANOSYLPURIN-6-YL)CARBAMOYL]THREONINE-5-MONOPHOSPHATE'>T6A</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=13fn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=13fn OCA], [https://pdbe.org/13fn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=13fn RCSB], [https://www.ebi.ac.uk/pdbsum/13fn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=13fn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TSAB_THEMA TSAB_THEMA] Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Kutchuashvili A]]
[[Category: Swairjo MA]]