View source for 1kez


==Crystal Structure of the Macrocycle-forming Thioesterase Domain of Erythromycin Polyketide Synthase (DEBS TE)==
<StructureSection load='1kez' size='340' side='right'caption='[[1kez]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1kez]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharopolyspora_erythraea Saccharopolyspora erythraea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KEZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kez OCA], [https://pdbe.org/1kez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kez RCSB], [https://www.ebi.ac.uk/pdbsum/1kez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kez ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ERYA3_SACER ERYA3_SACER] 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ke/1kez_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kez ConSurf].
<div style="clear:both"></div>

==See Also==
*[[6-deoxyerythronolide B synthase 3D structures|6-deoxyerythronolide B synthase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharopolyspora erythraea]]
[[Category: Cane DE]]
[[Category: Chen JC-H]]
[[Category: Foster PG]]
[[Category: Gokhale R]]
[[Category: Khosla C]]
[[Category: Krucinski J]]
[[Category: Miercke LJW]]
[[Category: Stroud RM]]
[[Category: Tsai S-C]]