View source for 1mh8


==Crystal Structure of a Phopholipase A2 Monomer with Isoleucine at Second Position==
<StructureSection load='1mh8' size='340' side='right'caption='[[1mh8]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1mh8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MH8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mh8 OCA], [https://pdbe.org/1mh8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mh8 RCSB], [https://www.ebi.ac.uk/pdbsum/1mh8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mh8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PA2B1_NAJSG PA2B1_NAJSG] PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mh/1mh8_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mh8 ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Naja sagittifera]]
[[Category: Jabeen T]]
[[Category: Jasti J]]
[[Category: Sharma S]]
[[Category: Singh N]]
[[Category: Singh RK]]
[[Category: Singh TP]]