View source for 1pmi


==Candida Albicans Phosphomannose Isomerase==
<StructureSection load='1pmi' size='340' side='right'caption='[[1pmi]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1pmi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PMI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PMI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pmi OCA], [https://pdbe.org/1pmi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pmi RCSB], [https://www.ebi.ac.uk/pdbsum/1pmi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pmi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MPI_CANAL MPI_CANAL] Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pm/1pmi_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pmi ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Candida albicans]]
[[Category: Large Structures]]
[[Category: Bernard AR]]
[[Category: Cleasby A]]
[[Category: Davies GJ]]
[[Category: Hubbard RE]]
[[Category: Payton MA]]
[[Category: Proudfoot AEI]]
[[Category: Skarzynski T]]
[[Category: Wells TNC]]
[[Category: Wonacott A]]