View source for 1qwx


==Crystal Structure of a Staphylococcal Inhibitor/Chaperone==
<StructureSection load='1qwx' size='340' side='right'caption='[[1qwx]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1qwx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MW2 Staphylococcus aureus subsp. aureus MW2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QWX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qwx OCA], [https://pdbe.org/1qwx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qwx RCSB], [https://www.ebi.ac.uk/pdbsum/1qwx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qwx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SSPC_STAAW SSPC_STAAW] Specifically inhibits the cysteine protease staphopain B (SspB) by blocking the active site of the enzyme. Probably required to protect cytoplasmic proteins from being degraded by prematurely activated/folded prostaphopain B. Also involved in growth capacity, viability and bacterial morphology (By similarity).
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</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus subsp. aureus MW2]]
[[Category: Brown CK]]
[[Category: Earhart CA]]
[[Category: Gu Z-Y]]
[[Category: McGavin MJ]]
[[Category: Nickerson N]]
[[Category: Ohlendorf DH]]