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==SOLUTION STRUCTURE OF AN UNUSUALLY STABLE RNA TETRAPLEX CONTAINING G-AND U-QUARTET STRUCTURES==
<StructureSection load='1rau' size='340' side='right'caption='[[1rau]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1rau]] is a 4 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RAU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rau OCA], [https://pdbe.org/1rau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rau RCSB], [https://www.ebi.ac.uk/pdbsum/1rau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rau ProSAT]</span></td></tr>
</table>
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== Publication Abstract from PubMed ==
A model for the solution structure of an RNA tetraplex, (rUGGGGU)4, has been obtained by two-dimensional NMR spectroscopy and molecular dynamics. The molecule is parallel stranded and Hoogsteen base-paired in 50 mM KCl, and it is so stable that three of its six imino protons have exchange half-lives measured in days at 40 degrees C. The tetraplex is stabilized by base stacking and by the hydrogen bonds in four G quartets and at least one U quartet. This is the first indication of the existence of U-quartet structures of which we are aware.

Solution structure of an unusually stable RNA tetraplex containing G- and U-quartet structures.,Cheong C, Moore PB Biochemistry. 1992 Sep 15;31(36):8406-14. PMID:1382577<ref>PMID:1382577</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 1rau" style="background-color:#fffaf0;"></div>
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Cheong C]]
[[Category: Moore PB]]