View source for 1row


==Structure of SSP-19, an MSP-domain protein like family member in Caenorhabditis elegans==
<StructureSection load='1row' size='340' side='right'caption='[[1row]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1row]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ROW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ROW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1row FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1row OCA], [https://pdbe.org/1row PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1row RCSB], [https://www.ebi.ac.uk/pdbsum/1row PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1row ProSAT], [https://www.topsan.org/Proteins/SECSG/1row TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SSP19_CAEEL SSP19_CAEEL] 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ro/1row_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1row ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Structural data are reported for SSP-19, a sperm-specific protein (SSP) family member from Caenorhabditis elegans. The SSP family [also known as the major sperm protein-like (MSP-like) family] contains proteins with only 107-109 amino acids, compared with 127 amino acids in the major sperm protein (MSP) family. MSP, the most abundant protein in nematode sperm, forms a dynamic actin-like cytoskeleton that provides the framework for the nematode sperm motility. In vivo, MSP dimers polymerize to form filaments that are constructed from two helical strands, which assemble into larger macromolecular structures. Little is known about the SSP family and a similar function is inferred from sequence and structural homology [Pfam (Protein Families Database of Alignments and HMMs) and SCOP (Structural Classification of Proteins) classification]. Despite the overall structural homology, the monomer-monomer interactions in SSP-19 are strikingly different from the interactions in the two MSP canonic domains described previously.

Structure of sperm-specific protein SSP-19 from Caenorhabditis elegans.,Schormann N, Symersky J, Luo M Acta Crystallogr D Biol Crystallogr. 2004 Oct;60(Pt 10):1840-5. Epub 2004, Sep 23. PMID:15388931<ref>PMID:15388931</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 1row" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Caenorhabditis elegans]]
[[Category: Large Structures]]
[[Category: Arabashi A]]
[[Category: Bunzel B]]
[[Category: Carson M]]
[[Category: DeLucas L]]
[[Category: Gray R]]
[[Category: Li S]]
[[Category: Lin G]]
[[Category: Lu S]]
[[Category: Luan C-H]]
[[Category: Luo D]]
[[Category: Luo M]]
[[Category: Nagy L]]
[[Category: Qiu S]]
[[Category: Schormann N]]
[[Category: Symersky J]]
[[Category: Zhang J]]