View source for 1sqw


==Crystal structure of KD93, a novel protein expressed in the human pro==
<StructureSection load='1sqw' size='340' side='right'caption='[[1sqw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1sqw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SQW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sqw OCA], [https://pdbe.org/1sqw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sqw RCSB], [https://www.ebi.ac.uk/pdbsum/1sqw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sqw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NIP7_HUMAN NIP7_HUMAN] Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.<ref>PMID:22195017</ref> 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sq/1sqw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sqw ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: An XM]]
[[Category: Chan WR]]
[[Category: Chen JR]]
[[Category: Jiang T]]
[[Category: Liang DC]]
[[Category: Liu JF]]
[[Category: Wang XQ]]
[[Category: Wang ZX]]