View source for 1tvj


==Solution Structure of chick cofilin==
<StructureSection load='1tvj' size='340' side='right'caption='[[1tvj]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1tvj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TVJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TVJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tvj OCA], [https://pdbe.org/1tvj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tvj RCSB], [https://www.ebi.ac.uk/pdbsum/1tvj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tvj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/COF2_CHICK COF2_CHICK] Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tv/1tvj_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tvj ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Gorbatyuk VY]]
[[Category: King GF]]
[[Category: Maciejewski MW]]
[[Category: Nosworthy NJ]]
[[Category: Robson SA]]
[[Category: Dos Remedios CG]]