View source for 1tyh


==Crystal Structure of Transcriptional Activator tenA from Bacillus subtilis==
<StructureSection load='1tyh' size='340' side='right'caption='[[1tyh]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1tyh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TYH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.54&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tyh OCA], [https://pdbe.org/1tyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tyh RCSB], [https://www.ebi.ac.uk/pdbsum/1tyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tyh ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1tyh TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TENA_BACSU TENA_BACSU] Stimulates the production of several extracellular degradative enzymes at the transcriptional level, probably by interfering with DegS and DegU, which are required for this effect. Is not an essential protein, but affects the sporulation frequency.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ty/1tyh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tyh ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Large Structures]]
[[Category: Burley SK]]
[[Category: Eswaramoorthy S]]
[[Category: Swaminathan S]]