View source for 1uhz


==Solution structure of dsRNA binding domain in Staufen homolog 2==
<StructureSection load='1uhz' size='340' side='right'caption='[[1uhz]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1uhz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UHZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uhz OCA], [https://pdbe.org/1uhz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uhz RCSB], [https://www.ebi.ac.uk/pdbsum/1uhz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uhz ProSAT], [https://www.topsan.org/Proteins/RSGI/1uhz TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/STAU2_MOUSE STAU2_MOUSE] RNA-binding protein required for the microtubule-dependent transport of neuronal RNA from the cell body to the dendrite. As protein synthesis occurs within the dendrite, the localization of specific mRNAs to dendrites may be a prerequisite for neurite outgrowth and plasticity at sites distant from the cell body (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uh/1uhz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uhz ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Aoki M]]
[[Category: Hayashizaki Y]]
[[Category: He F]]
[[Category: Hirota H]]
[[Category: Inoue M]]
[[Category: Kigawa T]]
[[Category: Koboyashi N]]
[[Category: Matsuda T]]
[[Category: Matsuo Y]]
[[Category: Muto Y]]
[[Category: Obayashi N]]
[[Category: Osanai T]]
[[Category: Seki E]]
[[Category: Shirouzu M]]
[[Category: Tanaka A]]
[[Category: Terada T]]
[[Category: Yabuki T]]
[[Category: Yokoyama S]]
[[Category: Yoshida M]]