View source for 1v5z


==Binding of coumarins to NAD(P)H:FMN oxidoreductase==
<StructureSection load='1v5z' size='340' side='right'caption='[[1v5z]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1v5z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aliivibrio_fischeri Aliivibrio fischeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5Z FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2HC:(2E)-3-(2-HYDROXYPHENYL)ACRYLIC+ACID'>2HC</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5z OCA], [https://pdbe.org/1v5z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5z RCSB], [https://www.ebi.ac.uk/pdbsum/1v5z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5z ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FRA1_ALIFS FRA1_ALIFS] Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction. Major FMN reductase. It is capable of using both NADH and NADPH as electron donors. As electron acceptor, FMN is the most effective, FAD is considerably effective, and riboflavin is the least effective.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v5z_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v5z ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Aliivibrio fischeri]]
[[Category: Large Structures]]
[[Category: Kobori T]]
[[Category: Koike H]]
[[Category: Saigo K]]
[[Category: Sasaki H]]
[[Category: Tanokura M]]
[[Category: Zenno S]]