View source for 1vte


==MOLECULAR STRUCTURE OF NICKED DNA. MODEL A4==
<StructureSection load='1vte' size='340' side='right'caption='[[1vte]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1vte]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VTE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vte OCA], [https://pdbe.org/1vte PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vte RCSB], [https://www.ebi.ac.uk/pdbsum/1vte PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vte ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The molecular structure of a nicked dodecamer DNA double helix, made of a ternary system containing d(CGCGAAAACGCG) + d(CGCGTT) + d(TTCGCG) oligonucleotides, has been determined by x-ray diffraction analysis at 3 A resolution. The molecule adopts a B-DNA conformation, not unlike those found in intact dodecamer DNA molecules crystallized in a somewhat different crystal lattice, despite a gap due to the absence of a phosphate group in the molecule. The helix has a distinct narrow minor groove near the center of the molecule at the AAAA region. This suggests that the internal stabilizing forces due to base stacking and hydrogen-bonding interactions are sufficient to overcome the loss of connectivity associated with the disruption of the covalent backbone of DNA.

Molecular structure of nicked DNA: a substrate for DNA repair enzymes.,Aymami J, Coll M, van der Marel GA, van Boom JH, Wang AH, Rich A Proc Natl Acad Sci U S A. 1990 Apr;87(7):2526-30. PMID:2320572<ref>PMID:2320572</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 1vte" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Aymani J]]
[[Category: Coll M]]
[[Category: Rich A]]
[[Category: Van Boom JH]]
[[Category: Van Der Marel GA]]
[[Category: Wang AH-J]]