View source for 1wmj


==Solution structure of Thioredoxin type h from Oryza sativa==
<StructureSection load='1wmj' size='340' side='right'caption='[[1wmj]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1wmj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WMJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WMJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wmj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wmj OCA], [https://pdbe.org/1wmj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wmj RCSB], [https://www.ebi.ac.uk/pdbsum/1wmj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wmj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRXH1_ORYSJ TRXH1_ORYSJ] Thiol-disulfide oxidoreductase involved in the redox regulation of MAP kinases. Under reducing conditions, inhibits MPK1 and MPK5 kinase activities. Mediates its own transport from cell-to-cell through plasmodesmata. Possesses insulin disulfide bonds reducing activity.<ref>PMID:19665023</ref> <ref>PMID:7766047</ref> <ref>PMID:9599802</ref> 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wm/1wmj_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wmj ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Thioredoxin 3D structures|Thioredoxin 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Oryza sativa]]
[[Category: Akagi K]]
[[Category: Inagaki F]]
[[Category: Katoh E]]
[[Category: Kumeta H]]
[[Category: Ogura H]]