View source for 1wru


==Structure of central hub elucidated by X-ray analysis of gene product 44; baseplate component of bacteriophage Mu==
<StructureSection load='1wru' size='340' side='right'caption='[[1wru]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1wru]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Mu Escherichia virus Mu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WRU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wru OCA], [https://pdbe.org/1wru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wru RCSB], [https://www.ebi.ac.uk/pdbsum/1wru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wru ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BP44_BPMU BP44_BPMU] Forms the central cylindrical hub of the baseplate and plays an important role in baseplate and tail assembly (Probable). Core component of the initiator complex that triggers the tail tube polymerization during tail assembly (Probable). Forms a conduit that probably functions as an extension of the tail tube allowing viral DNA release during ejection. Might facilitate the interaction of the virus with the host cell surface through electrostatic interactions during virus entry into host cell.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wr/1wru_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wru ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Escherichia virus Mu]]
[[Category: Large Structures]]
[[Category: Kawano K]]
[[Category: Kitazawa D]]
[[Category: Kondou Y]]
[[Category: Mizuguchi M]]
[[Category: Takeda S]]
[[Category: Tsukihara T]]
[[Category: Yamashita E]]