View source for 1zvn


==Crystal structure of chick MN-cadherin EC1==
<StructureSection load='1zvn' size='340' side='right'caption='[[1zvn]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1zvn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZVN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZVN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.16&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zvn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zvn OCA], [https://pdbe.org/1zvn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zvn RCSB], [https://www.ebi.ac.uk/pdbsum/1zvn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zvn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAD20_CHICK CAD20_CHICK] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.<ref>PMID:12007407</ref> <ref>PMID:15992777</ref> <ref>PMID:16564015</ref> 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zv/1zvn_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zvn ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Cadherin 3D structures|Cadherin 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Bahna F]]
[[Category: Chen CP]]
[[Category: Ciatto C]]
[[Category: Honig B]]
[[Category: Jessell TM]]
[[Category: Patel SD]]
[[Category: Price SR]]
[[Category: Rajebhosale M]]
[[Category: Schieren I]]
[[Category: Shapiro L]]