View source for 23sq


==TamA complex with TamB DUF490 in detergent micelles.==
<StructureSection load='23sq' size='340' side='right'caption='[[23sq]], [[Resolution|resolution]] 3.51&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[23sq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=23SQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=23SQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.51&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=23sq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=23sq OCA], [https://pdbe.org/23sq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=23sq RCSB], [https://www.ebi.ac.uk/pdbsum/23sq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=23sq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TAMB_ECOLI TAMB_ECOLI] Part of the translocation and assembly module (TAM) autotransporter assembly complex, which functions in translocation of autotransporters across the outer membrane (PubMed:22466966). In reconstituted TAM this subunit (Ag43, AC P39180) is not necessary for substrate penetration in the outer membrane. Substrate binding to TamA moves its POTRA domains about 30 Angstroms into the periplasm, which would deform either the outer membrane or TamB and may provide force to reset TAM (PubMed:25341963).<ref>PMID:22466966</ref> <ref>PMID:25341963</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Adamson LSR]]
[[Category: Doyle MT]]
[[Category: Grosas AB]]