View source for 2crq


==Solution structure of C-terminal domain of RIKEN cDNA 2810012L14==
<StructureSection load='2crq' size='340' side='right'caption='[[2crq]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2crq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CRQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CRQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2crq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2crq OCA], [https://pdbe.org/2crq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2crq RCSB], [https://www.ebi.ac.uk/pdbsum/2crq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2crq ProSAT], [https://www.topsan.org/Proteins/RSGI/2crq TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IF3M_MOUSE IF3M_MOUSE] IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cr/2crq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2crq ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Hayashi F]]
[[Category: Nagashima T]]
[[Category: Yokoyama S]]