View source for 2ct5


==Solution Structure of the zinc finger BED domain of the zinc finger BED domain containing protein 1==
<StructureSection load='2ct5' size='340' side='right'caption='[[2ct5]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ct5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CT5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ct5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ct5 OCA], [https://pdbe.org/2ct5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ct5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ct5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ct5 ProSAT], [https://www.topsan.org/Proteins/RSGI/2ct5 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ZBED1_HUMAN ZBED1_HUMAN] Binds to 5'-TGTCG[CT]GA[CT]A-3' DNA elements found in the promoter regions of a number of genes related to cell proliferation. Binds to the histone H1 promoter and stimulates transcription. Was first identified as gene weakly similar to Ac transposable elements, but does not code for any transposase activity.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Inoue M]]
[[Category: Kigawa T]]
[[Category: Koshiba S]]
[[Category: Miyamoto K]]
[[Category: Tomizawa T]]
[[Category: Yokoyama S]]