View source for 2cvc


==Crystal structure of High-Molecular Weight Cytochrome c from Desulfovibrio vulgaris (Hildenborough)==
<StructureSection load='2cvc' size='340' side='right'caption='[[2cvc]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2cvc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CVC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CVC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cvc OCA], [https://pdbe.org/2cvc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cvc RCSB], [https://www.ebi.ac.uk/pdbsum/2cvc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cvc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HMWC_NITV2 HMWC_NITV2] HMWC (high-molecular-weight cytochrome c), ORF2, ORF3, ORF4, ORF5 and ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cv/2cvc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cvc ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
__TOC__
</StructureSection>
[[Category: Desulfovibrio vulgaris]]
[[Category: Large Structures]]
[[Category: Akutsu H]]
[[Category: Higuchi Y]]
[[Category: Kitamura M]]
[[Category: Morimoto Y]]
[[Category: Ozawa K]]
[[Category: Sato M]]
[[Category: Shibata N]]
[[Category: Suto K]]
[[Category: Takayama Y]]
[[Category: Yasuoka N]]