View source for 2dbo


==Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Aquifex aeolicus==
<StructureSection load='2dbo' size='340' side='right'caption='[[2dbo]], [[Resolution|resolution]] 2.76&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2dbo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DBO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DBO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.76&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dbo OCA], [https://pdbe.org/2dbo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dbo RCSB], [https://www.ebi.ac.uk/pdbsum/2dbo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dbo ProSAT], [https://www.topsan.org/Proteins/RSGI/2dbo TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DTD_AQUAE DTD_AQUAE] Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/db/2dbo_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dbo ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Aquifex aeolicus VF5]]
[[Category: Large Structures]]
[[Category: Bessho Y]]
[[Category: Ishii T]]
[[Category: Shibata R]]
[[Category: Shirouzu M]]
[[Category: Yokoyama S]]