View source for 2dlu


==Solution structure of the second PDZ domain of human InaD-like protein==
<StructureSection load='2dlu' size='340' side='right'caption='[[2dlu]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2dlu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DLU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DLU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dlu OCA], [https://pdbe.org/2dlu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dlu RCSB], [https://www.ebi.ac.uk/pdbsum/2dlu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dlu ProSAT], [https://www.topsan.org/Proteins/RSGI/2dlu TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/INADL_HUMAN INADL_HUMAN] Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons.<ref>PMID:11927608</ref> 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dl/2dlu_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dlu ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Hayashi F]]
[[Category: Inoue K]]
[[Category: Izumi K]]
[[Category: Kurosaki C]]
[[Category: Yokoyama S]]
[[Category: Yoshida M]]