View source for 2dyq


==Crystal Structure of the C-terminal Phophotyrosine Interaction Domain of Human APBB3==
<StructureSection load='2dyq' size='340' side='right'caption='[[2dyq]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2dyq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DYQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyq OCA], [https://pdbe.org/2dyq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dyq RCSB], [https://www.ebi.ac.uk/pdbsum/2dyq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dyq ProSAT], [https://www.topsan.org/Proteins/RSGI/2dyq TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/APBB3_HUMAN APBB3_HUMAN] May modulate the internalization of beta-amyloid precursor protein.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dy/2dyq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dyq ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Kishishita S]]
[[Category: Nishino A]]
[[Category: Saijo S]]
[[Category: Shirouzu M]]
[[Category: Yokoyama S]]