View source for 2i18


==The refined structure of C-terminal domain of an EF-hand Calcium binding Protein from Entamoeba Histolytica==
<StructureSection load='2i18' size='340' side='right'caption='[[2i18]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2i18]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Entamoeba_histolytica Entamoeba histolytica]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ev7 2ev7]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I18 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I18 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LA:LANTHANUM+(III)+ION'>LA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i18 OCA], [https://pdbe.org/2i18 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i18 RCSB], [https://www.ebi.ac.uk/pdbsum/2i18 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i18 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CALBP_ENTHI CALBP_ENTHI] Could play a role in the transduction of secondary messages on binding of calcium.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i1/2i18_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i18 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Entamoeba histolytica]]
[[Category: Large Structures]]
[[Category: Chary KVR]]
[[Category: Mukherjee S]]
[[Category: Mustafi SM]]