View source for 2jgy


==The crystal structure of human orotidine-5'-decarboxylase domain of human uridine monophosphate synthetase (UMPS)==
<StructureSection load='2jgy' size='340' side='right' caption='[[2jgy]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2jgy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JGY FirstGlance]. <br>
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgy OCA], [http://pdbe.org/2jgy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jgy RCSB], [http://www.ebi.ac.uk/pdbsum/2jgy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jgy ProSAT]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jg/2jgy_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jgy ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]]
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Arrowsmith, C]]
[[Category: Berg, S van den]]
[[Category: Berglund, H]]
[[Category: Busam, R]]
[[Category: Collins, R]]
[[Category: Dahlgren, L G]]
[[Category: Edwards, A]]
[[Category: Ericsson, U B]]
[[Category: Flodin, S]]
[[Category: Flores, A]]
[[Category: Graslund, S]]
[[Category: Hallberg, B M]]
[[Category: Hammarstrom, M]]
[[Category: Holmberg-Schiavone, L]]
[[Category: Johansson, I]]
[[Category: Karlberg, T]]
[[Category: Kosinska, U]]
[[Category: Kotenyova, T]]
[[Category: Lehtio, L]]
[[Category: Moche, M]]
[[Category: Nilsson, M E]]
[[Category: Nordlund, P]]
[[Category: Nyman, T]]
[[Category: Ogg, D]]
[[Category: Persson, C]]
[[Category: Structural genomic]]
[[Category: Sagemark, J]]
[[Category: Stenmark, P]]
[[Category: Sundstrom, M]]
[[Category: Thorsell, A G]]
[[Category: Uppenberg, J]]
[[Category: Upsten, M]]
[[Category: Weigelt, J]]
[[Category: Decarboxylase]]
[[Category: Disease mutation]]
[[Category: Glycosyltransferase]]
[[Category: Lyase]]
[[Category: Multifunctional enzyme]]
[[Category: Orotidine-5'-decarboxylase]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Tim barrel dimer]]
[[Category: Transferase]]