View source for 2jqp


==NMR structure determination of Bungatoxin from Bungarus candidus (Malayan Krait)==
<StructureSection load='2jqp' size='340' side='right'caption='[[2jqp]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2jqp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bungarus_candidus Bungarus candidus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JQP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jqp OCA], [https://pdbe.org/2jqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jqp RCSB], [https://www.ebi.ac.uk/pdbsum/2jqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jqp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/3NO21_BUNCA 3NO21_BUNCA] Binds with low affinity to muscular (alpha-1-beta-1-epsilon-delta/CHRNA1-CHRNB1-CHRNE-CHRND) and very low affinity to neuronal (alpha7) nicotinic acetylcholine receptor (nAChR).[UniProtKB:O42255]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jq/2jqp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jqp ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Bungarus candidus]]
[[Category: Large Structures]]
[[Category: Jois SD]]
[[Category: Kini RM]]
[[Category: Ramos AT]]
[[Category: Troncone LRP]]
[[Category: Ujikawa GY]]
[[Category: Vivekanandan S]]
[[Category: De Magalhaes L]]