View source for 2khb


==Solution structure of linear kalata B1 (loop 6)==
<StructureSection load='2khb' size='340' side='right'caption='[[2khb]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2khb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oldenlandia_affinis Oldenlandia affinis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KHB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KHB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2khb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2khb OCA], [https://pdbe.org/2khb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2khb RCSB], [https://www.ebi.ac.uk/pdbsum/2khb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2khb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KAB1_OLDAF KAB1_OLDAF] Probably participates in a plant defense mechanism. Has antibiotic activity. Has a diuretic effect. Has a uterotonic effect in humans. Active against the Gram-positive S.aureus with a minimum inhibition concentration of approximately 0.2 microM. Relatively ineffective against Gram-negative bacteria such as E.coli and P.aeruginosa. Inhibitory effect on the growth and development of larvae from H.punctigera. The unmodified form has hemolytic activity, the oxidized form lacks hemolytic activity. If the protein is linearized, hemolytic activity is lost.<ref>PMID:17534989</ref> <ref>PMID:12779323</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Oldenlandia affinis]]
[[Category: Craik DJ]]
[[Category: Wang CK]]