View source for 2krm


==RDC refined solution structure of the first SH3 domain of CD2AP==
<StructureSection load='2krm' size='340' side='right'caption='[[2krm]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2krm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krm OCA], [https://pdbe.org/2krm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krm RCSB], [https://www.ebi.ac.uk/pdbsum/2krm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CD2AP_MOUSE CD2AP_MOUSE] Required for cytokinesis (By similarity). Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus.<ref>PMID:10514378</ref> 

==See Also==
*[[CD2-associated protein 3D structures|CD2-associated protein 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Azuaga AI]]
[[Category: Ortega Roldan JAJ]]
[[Category: Van Nuland NAJ]]