View source for 2krx


==Solution NMR Structure of asl3597 from Nostoc sp. PCC7120. Northeast Structural Genomics Consortium Target ID Nsr244.==
<StructureSection load='2krx' size='340' side='right'caption='[[2krx]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2krx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_sp._PCC_7120_=_FACHB-418 Nostoc sp. PCC 7120 = FACHB-418]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krx OCA], [https://pdbe.org/2krx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krx RCSB], [https://www.ebi.ac.uk/pdbsum/2krx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8YR53_NOSS1 Q8YR53_NOSS1] 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/2krx_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2krx ConSurf].
<div style="clear:both"></div>
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== Publication Abstract from PubMed ==
The protein domain family PF12095 (DUF3571) is a functionally uncharacterized family of small proteins conserved from cyanobacteria to plants that are typically 85 to 95 amino acids in length in cyanobacteria. In this report, we describe the solution NMR structure of the 86-residue protein Asl3597 from Nostoc sp. PCC7120. The structure of Asl3597, which constitutes the first three-dimensional structure from protein family PF12095, has a unique alpha/beta sandwich fold consisting of four anti-parallel beta-strands opposite three continuous alpha-helices. Asl3597 may have a role in the assembly of the hydrophilic subcomplex of the cyanobacterial NAD(P)H complex as suggested by data for the orthologous Chlororespiratory reduction 7 protein from Arabidopsis thaliana.

Solution NMR structure of Asl3597 from Nostoc sp. PCC7120, the first structure from protein domain family PF12095, reveals a novel fold.,Feldmann EA, Ramelot TA, Yang Y, Xiao R, Acton TB, Everett JK, Montelione GT, Kennedy MA Proteins. 2012 Feb;80(2):671-5. doi: 10.1002/prot.23236. Epub 2011 Nov 24. PMID:22113821<ref>PMID:22113821</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2krx" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Nostoc sp. PCC 7120 = FACHB-418]]
[[Category: Acton T]]
[[Category: Ciccosanti C]]
[[Category: Everett JK]]
[[Category: Feldmann EA]]
[[Category: Janjua HA]]
[[Category: Kennedy MA]]
[[Category: Lee DK]]
[[Category: Liu J]]
[[Category: Montelione GT]]
[[Category: Ramelot TA]]
[[Category: Rost B]]
[[Category: Xiao R]]
[[Category: Yang Y]]