View source for 2kt5


==RRM domain of mRNA export adaptor REF2-I bound to HSV-1 ICP27 peptide==
<StructureSection load='2kt5' size='340' side='right'caption='[[2kt5]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2kt5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_1 Human alphaherpesvirus 1] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KT5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kt5 OCA], [https://pdbe.org/2kt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kt5 RCSB], [https://www.ebi.ac.uk/pdbsum/2kt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kt5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ALRF2_MOUSE ALRF2_MOUSE] Export adapter involved in spliced and unspliced mRNA nuclear export. Binds mRNA which is transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway); enhances NXF1-NXT1 RNA-binding activity.<ref>PMID:10786854</ref> <ref>PMID:11158589</ref> <ref>PMID:18364396</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Human alphaherpesvirus 1]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Golovanov AP]]
[[Category: Hautbergue GM]]
[[Category: Tunnicliffe NB]]
[[Category: Wilson SA]]