View source for 2kv8


==Solution structure ofRGS12 PDZ domain==
<StructureSection load='2kv8' size='340' side='right'caption='[[2kv8]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2kv8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KV8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kv8 OCA], [https://pdbe.org/2kv8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kv8 RCSB], [https://www.ebi.ac.uk/pdbsum/2kv8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kv8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RGS12_HUMAN RGS12_HUMAN] Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.

==See Also==
*[[Regulator of G-protein signaling 3D structures|Regulator of G-protein signaling 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Huang H]]
[[Category: Ji P]]
[[Category: Lu G]]