View source for 2kx3


==The solution structure of the mutant of UBL domain of UBLCP1, I5M==
<StructureSection load='2kx3' size='340' side='right'caption='[[2kx3]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2kx3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KX3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kx3 OCA], [https://pdbe.org/2kx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kx3 RCSB], [https://www.ebi.ac.uk/pdbsum/2kx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kx3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/UBCP1_HUMAN UBCP1_HUMAN] Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.<ref>PMID:15883030</ref> <ref>PMID:21949367</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Ko S]]
[[Category: Lee N]]