View source for 2l8r


==Solution structure of human protein C6orf130 in complex with ADP-ribose==
<StructureSection load='2l8r' size='340' side='right'caption='[[2l8r]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2l8r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L8R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L8R FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APR:ADENOSINE-5-DIPHOSPHORIBOSE'>APR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l8r OCA], [https://pdbe.org/2l8r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l8r RCSB], [https://www.ebi.ac.uk/pdbsum/2l8r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l8r ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OARD1_HUMAN OARD1_HUMAN] Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Catalyzes the deacylation of O-acetyl-ADP-ribose, O-propionyl-ADP-ribose and O-butyryl-ADP-ribose, yielding ADP-ribose plus acetate, propionate and butyrate, respectively.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Lytle BL]]
[[Category: Peterson FC]]
[[Category: Volkman BF]]