View source for 2ldu


==Solution NMR Structure of Heat shock factor protein 1 DNA binding domain from homo sapiens, Northeast Structural Genomics Consortium Target HR3023C==
<StructureSection load='2ldu' size='340' side='right'caption='[[2ldu]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ldu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LDU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LDU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ldu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ldu OCA], [https://pdbe.org/2ldu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ldu RCSB], [https://www.ebi.ac.uk/pdbsum/2ldu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ldu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HSF1_HUMAN HSF1_HUMAN] DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.<ref>PMID:11447121</ref> <ref>PMID:8946918</ref> <ref>PMID:9121459</ref> <ref>PMID:9535852</ref> <ref>PMID:11583998</ref> <ref>PMID:12659875</ref> <ref>PMID:12665592</ref> <ref>PMID:16278218</ref> 

==See Also==
*[[Heat shock factor|Heat shock factor]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Acton TB]]
[[Category: Ciccosanti C]]
[[Category: Everett JK]]
[[Category: Huang YB]]
[[Category: Janjua H]]
[[Category: Lee H]]
[[Category: Liu G]]
[[Category: Montelione GT]]
[[Category: Wang HB]]
[[Category: Xiao R]]