View source for 2lj1


==The third SH3 domain of R85FL with ataxin-7 PRR==
<StructureSection load='2lj1' size='340' side='right'caption='[[2lj1]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2lj1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LJ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LJ1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lj1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lj1 OCA], [https://pdbe.org/2lj1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lj1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lj1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lj1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SRBS1_HUMAN SRBS1_HUMAN] Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity).[UniProtKB:Q62417]
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Hu H]]
[[Category: Jiang Y]]