View source for 2lll


==Solution NMR structure of C-terminal globular domain of human Lamin-B2, Northeast Structural Genomics Consortium target HR8546A==
<StructureSection load='2lll' size='340' side='right'caption='[[2lll]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2lll]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LLL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LLL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lll FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lll OCA], [https://pdbe.org/2lll PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lll RCSB], [https://www.ebi.ac.uk/pdbsum/2lll PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lll ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/LMNB2_HUMAN LMNB2_HUMAN] Partial acquired lipodystrophy. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/LMNB2_HUMAN LMNB2_HUMAN] Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith C]]
[[Category: Garcia M]]
[[Category: Houliston S]]
[[Category: Lemak A]]
[[Category: Min J]]
[[Category: Montelione GT]]
[[Category: Xu C]]
[[Category: Yee A]]