View source for 2lqr


==NMR structure of Ig3 domain of palladin==
<StructureSection load='2lqr' size='340' side='right'caption='[[2lqr]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2lqr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LQR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lqr OCA], [https://pdbe.org/2lqr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lqr RCSB], [https://www.ebi.ac.uk/pdbsum/2lqr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lqr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PALLD_MOUSE PALLD_MOUSE] Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific May be required for the initiation of neural tube closure.<ref>PMID:10931874</ref> <ref>PMID:15950489</ref> <ref>PMID:16492705</ref> <ref>PMID:17115415</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Beck MR]]
[[Category: Campbell SL]]
[[Category: Dixon IV RDS]]
[[Category: Murphy GS]]
[[Category: Otey CA]]