View source for 2mhw


==The solution NMR structure of maximin-4 in SDS micelles==
<StructureSection load='2mhw' size='340' side='right'caption='[[2mhw]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2mhw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bombina_maxima Bombina maxima]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MHW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MHW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mhw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mhw OCA], [https://pdbe.org/2mhw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mhw RCSB], [https://www.ebi.ac.uk/pdbsum/2mhw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mhw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/M4H33_BOMMX M4H33_BOMMX] Maximin-4 shows antibacterial activity against both Gram-positive and Gram-negative bacteria. It shows also antimicrobial activity against the fungus C.albicans, but not against A.flavus nor P.uticale. It has little hemolytic activity. It does not possess a significant cytotoxicity against tumor cell lines. It does not possess a significant anti-HIV activity.  Maximin-H3 shows antibacterial activity against both Gram-positive and Gram-negative bacteria. It shows also antimicrobial activity against the fungus C.albicans. Shows strong hemolytic activity.
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</StructureSection>
[[Category: Bombina maxima]]
[[Category: Large Structures]]
[[Category: Banoczi Z]]
[[Category: Burck J]]
[[Category: Heinzmann R]]
[[Category: Hudecz F]]
[[Category: Kiraly P]]
[[Category: Toke O]]
[[Category: Ulrich AS]]