View source for 2moc


==Membrane induced structure of novel human tachykinin Hemokinin-1 (hHK1)==
<StructureSection load='2moc' size='340' side='right'caption='[[2moc]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2moc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MOC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MOC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2moc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2moc OCA], [https://pdbe.org/2moc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2moc RCSB], [https://www.ebi.ac.uk/pdbsum/2moc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2moc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TKN4_HUMAN TKN4_HUMAN] Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin-C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility.<ref>PMID:12716968</ref> <ref>PMID:17101218</ref> <ref>PMID:17437961</ref> <ref>PMID:17655832</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Cowsik S]]
[[Category: Ganjiwale A]]