View source for 2muj


==Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria==
<StructureSection load='2muj' size='340' side='right'caption='[[2muj]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2muj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_FCR-3/Gambia Plasmodium falciparum FCR-3/Gambia]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MUJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MUJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2muj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2muj OCA], [https://pdbe.org/2muj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2muj RCSB], [https://www.ebi.ac.uk/pdbsum/2muj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2muj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/T1RTG8_PLAFA T1RTG8_PLAFA] 
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Three Plasmodium falciparum serine repeat antigen (SERA) protein peptides were studied by NMR and structure calculations being done in 70:30 water:trifluoroethanol solution. Peptide 22834 was shown to be immunogenic and protective against malaria in Aotus monkeys, whilst native peptide 6737 and its analogue 14096 did not present protection against the disease in these monkeys. Results showed a relationship between these peptides' secondary structure and their function as immunogen against malaria.

Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria.,Cubillos M, Alba MP, Bermudez A, Trujillo M, Patarroyo ME Biochimie. 2003 Jul;85(7):651-7. PMID:14505820<ref>PMID:14505820</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2muj" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Plasmodium falciparum FCR-3/Gambia]]
[[Category: Alba M]]
[[Category: Bermudez A]]
[[Category: Cubillos M]]
[[Category: Patarroyo ME]]
[[Category: Trujillo M]]